@article{32, author = {Marcela Monaco and Joshua Stein and Sushma Naithani and Sharon Wei and Palitha Dharmawardhana and Sunita Kumari and Vindhya Amarasinghe and Ken Youens-Clark and James Thomason and Justin Preece and Shiran Pasternak and Andrew Olson and Yinping Jiao and Zhenyuan Lu and Dan Bolser and Arnaud Kerhornou and Dan Staines and Brandon Walts and Guanming Wu and Peter D'Eustachio and Robin Haw and David Croft and Paul Kersey and Lincoln Stein and Pankaj Jaiswal and Doreen Ware}, title = {Gramene 2013: comparative plant genomics resources.}, abstract = {Gramene (http://www.gramene.org) is a curated online resource for comparative functional genomics in crops and model plant species, currently hosting 27 fully and 10 partially sequenced reference genomes in its build number 38. Its strength derives from the application of a phylogenetic framework for genome comparison and the use of ontologies to integrate structural and functional annotation data. Whole-genome alignments complemented by phylogenetic gene family trees help infer syntenic and orthologous relationships. Genetic variation data, sequences and genome mappings available for 10 species, including Arabidopsis, rice and maize, help infer putative variant effects on genes and transcripts. The pathways section also hosts 10 species-specific metabolic pathways databases developed in-house or by our collaborators using Pathway Tools software, which facilitates searches for pathway, reaction and metabolite annotations, and allows analyses of user-defined expression datasets. Recently, we released a Plant Reactome portal featuring 133 curated rice pathways. This portal will be expanded for Arabidopsis, maize and other plant species. We continue to provide genetic and QTL maps and marker datasets developed by crop researchers. The project provides a unique community platform to support scientific research in plant genomics including studies in evolution, genetics, plant breeding, molecular biology, biochemistry and systems biology.}, year = {2014}, journal = {Nucleic acids research}, volume = {42}, pages = {D1193-9}, month = {2014 Jan}, issn = {1362-4962}, doi = {10.1093/nar/gkt1110}, language = {eng}, }