@article{85, keywords = {Computational Biology, Databases, Genetic, Gene Regulatory Networks, Genomics, Humans, Metabolic Networks and Pathways, Metabolomics, Plants, Proteomics, Signal Transduction, Web Browser}, author = {Sushma Naithani and Parul Gupta and Justin Preece and Peter D'Eustachio and Justin Elser and Priyanka Garg and Daemon Dikeman and Jason Kiff and Justin Cook and Andrew Olson and Sharon Wei and Marcela Tello-Ruiz and Antonio Mundo and Alfonso Munoz-Pomer and Suhaib Mohammed and Tiejun Cheng and Evan Bolton and Irene Papatheodorou and Lincoln Stein and Doreen Ware and Pankaj Jaiswal}, title = {Plant Reactome: a knowledgebase and resource for comparative pathway analysis.}, abstract = {

Plant Reactome (https://plantreactome.gramene.org) is an open-source, comparative plant pathway knowledgebase of the Gramene project. It uses Oryza sativa (rice) as a reference species for manual curation of pathways and extends pathway knowledge to another 82 plant species via gene-orthology projection using the Reactome data model and framework. It currently hosts 298 reference pathways, including metabolic and transport pathways, transcriptional networks, hormone signaling pathways, and plant developmental processes. In addition to browsing plant pathways, users can upload and analyze their omics data, such as the gene-expression data, and overlay curated or experimental gene-gene interaction data to extend pathway knowledge. The curation team actively engages researchers and students on gene and pathway curation by offering workshops and online tutorials. The Plant Reactome supports, implements and collaborates with the wider community to make data and tools related to genes, genomes, and pathways Findable, Accessible, Interoperable and Re-usable (FAIR).

}, year = {2020}, journal = {Nucleic Acids Res}, volume = {48}, pages = {D1093-D1103}, month = {2020 Jan 08}, issn = {1362-4962}, doi = {10.1093/nar/gkz996}, language = {eng}, }