03920nas a2201105   4500000000100000000000100001008004100002260001600043100002100059700002300080700001800103700001800121700001800139700001800157700001800175700002000193700001400213700001600227700002000243700001700263700002300280700002100303700001700324700001800341700001700359700002400376700001600400700002200416700002500438700001900463700001900482700001900501700002300520700001800543700001700561700001700578700002500595700001400620700001200634700001800646700001900664700001800683700001800701700002600719700001700745700002000762700002200782700001800804700002500822700001800847700001700865700002400882700001700906700002000923700001700943700001900960700001700979700002100996700002601017700001601043700002501059700002001084700002601104700002101130700001801151700001901169700001601188700001701204700002701221700002301248700001901271700002101290700002001311700002401331700001801355700001901373700002301392700001501415700001901430700001701449700002001466700001901486700001901505700003101524700001901555700002101574700001901595700001901614245003801633856007401671300001101745490000801756520103601764022001402800       2014                            d  c2014 Jun 191 aAlexander Myburg1 aDario Grattapaglia1 aGerald Tuskan1 aUffe Hellsten1 aRichard Hayes1 aJane Grimwood1 aJerry Jenkins1 aErika Lindquist1 aHope Tice1 aDiane Bauer1 aDavid Goodstein1 aInna Dubchak1 aAlexandre Poliakov1 aEshchar Mizrachi1 aAnand Kullan1 aSteven Hussey1 aDesre Pinard1 aKaren van der Merwe1 aPooja Singh1 aIda van Jaarsveld1 aOrzenil Silva-Junior1 aRoberto Togawa1 aMarilia Pappas1 aDanielle Faria1 aCarolina Sansaloni1 aCesar Petroli1 aXiaohan Yang1 aPriya Ranjan1 aTimothy Tschaplinski1 aChu-Yu Ye1 aTing Li1 aLieven Sterck1 aKevin Vanneste1 aFlorent Murat1 aMarçal Soler1 aHélène San Clemente1 aNaijib Saidi1 aHua Cassan-Wang1 aChristophe Dunand1 aCharles Hefer1 aErich Bornberg-Bauer1 aAnna Kersting1 aKelly Vining1 aVindhya Amarasinghe1 aMartin Ranik1 aSushma Naithani1 aJustin Elser1 aAlexander Boyd1 aAaron Liston1 aJoseph Spatafora1 aPalitha Dharmwardhana1 aRajani Raja1 aChristopher Sullivan1 aElisson Romanel1 aMarcio Alves-Ferreira1 aCarsten Külheim1 aWilliam Foley1 aVictor Carocha1 aJorge Paiva1 aDavid Kudrna1 aSergio Brommonschenkel1 aGiancarlo Pasquali1 aMargaret Byrne1 aPhilippe Rigault1 aJosquin Tibbits1 aAntanas Spokevicius1 aRebecca Jones1 aDorothy Steane1 aRené Vaillancourt1 aBrad Potts1 aFourie Joubert1 aKerrie Barry1 aGeorgios Pappas1 aSteven Strauss1 aPankaj Jaiswal1 aJacqueline Grima-Pettenati1 aJérôme Salse1 aYves Van de Peer1 aDaniel Rokhsar1 aJeremy Schmutz00aThe genome of Eucalyptus grandis.  uhttp://www.nature.com/nature/journal/v510/n7505/full/nature13308.html  a356-620 v5103 aEucalypts are the world's most widely planted hardwood trees. Their outstanding diversity, adaptability and growth have made them a global renewable resource of fibre and energy. We sequenced and assembled >94% of the 640-megabase genome of Eucalyptus grandis. Of 36,376 predicted protein-coding genes, 34% occur in tandem duplications, the largest proportion thus far in plant genomes. Eucalyptus also shows the highest diversity of genes for specialized metabolites such as terpenes that act as chemical defence and provide unique pharmaceutical oils. Genome sequencing of the E. grandis sister species E. globulus and a set of inbred E. grandis tree genomes reveals dynamic genome evolution and hotspots of inbreeding depression. The E. grandis genome is the first reference for the eudicot order Myrtales and is placed here sister to the eurosids. This resource expands our understanding of the unique biology of large woody perennials and provides a powerful tool to accelerate comparative biology, breeding and biotechnology.  a1476-4687