02731nas a2200517   4500000000100000000000100001008004100002260001500043100002300058700001700081700001500098700001800113700001700131700002000148700002400168700002700192700001700219700002000236700001800256700002000274700001700294700001200311700001900323700001800342700002100360700001800381700001700399700001700416700001600433700001300449700002000462700002100482700001800503700001600521700002200537700001800559700002100577700001600598700001900614700001600633245006800649300001300717490000700730520146200737022001402199       2016                            d  c2016 Jan 41 aMarcela Tello-Ruiz1 aJoshua Stein1 aSharon Wei1 aJustin Preece1 aAndrew Olson1 aSushma Naithani1 aVindhya Amarasinghe1 aPalitha Dharmawardhana1 aYinping Jiao1 aJoseph Mulvaney1 aSunita Kumari1 aKapeel Chougule1 aJustin Elser1 aBo Wang1 aJames Thomason1 aDaniel Bolser1 aArnaud Kerhornou1 aBrandon Walts1 aNuno Fonseca1 aLaura Huerta1 aMaria Keays1 aAmy Tang1 aHelen Parkinson1 aAntonio Fabregat1 aSheldon McKay1 aJoel Weiser1 aPeter D'Eustachio1 aLincoln Stein1 aRobert Petryszak1 aPaul Kersey1 aPankaj Jaiswal1 aDoreen Ware00aGramene 2016: comparative plant genomics and pathway resources.  aD1133-400 v443 aGramene (http://www.gramene.org) is an online resource for comparative functional genomics in crops and model plant species. Its two main frameworks are genomes (collaboration with Ensembl Plants) and pathways (The Plant Reactome and archival BioCyc databases). Since our last NAR update, the database website adopted a new Drupal management platform. The genomes section features 39 fully assembled reference genomes that are integrated using ontology-based annotation and comparative analyses, and accessed through both visual and programmatic interfaces. Additional community data, such as genetic variation, expression and methylation, are also mapped for a subset of genomes. The Plant Reactome pathway portal (http://plantreactome.gramene.org) provides a reference resource for analyzing plant metabolic and regulatory pathways. In addition to ∼200 curated rice reference pathways, the portal hosts gene homology-based pathway projections for 33 plant species. Both the genome and pathway browsers interface with the EMBL-EBI's Expression Atlas to enable the projection of baseline and differential expression data from curated expression studies in plants. Gramene's archive website (http://archive.gramene.org) continues to provide previously reported resources on comparative maps, markers and QTL. To further aid our users, we have also introduced a live monthly educational webinar series and a Gramene YouTube channel carrying video tutorials.  a1362-4962