02394nas a2200517 4500000000100000000000100001008004100002260001600043653002600059653002300085653002900108653001300137653001100150653003600161653001700197653001100214653001500225653002400240653001600264100002000280700001600300700001800316700002200334700001700356700001800373700001900391700001500410700001600425700001700441700001500458700002300473700001800496700002400514700002000538700001700558700001600575700002400591700001800615700001600633700001900649245008300668300001600751490000700767520108800774022001401862 2020 d c2020 Jan 0810aComputational Biology10aDatabases, Genetic10aGene Regulatory Networks10aGenomics10aHumans10aMetabolic Networks and Pathways10aMetabolomics10aPlants10aProteomics10aSignal Transduction10aWeb Browser1 aSushma Naithani1 aParul Gupta1 aJustin Preece1 aPeter D'Eustachio1 aJustin Elser1 aPriyanka Garg1 aDaemon Dikeman1 aJason Kiff1 aJustin Cook1 aAndrew Olson1 aSharon Wei1 aMarcela Tello-Ruiz1 aAntonio Mundo1 aAlfonso Munoz-Pomer1 aSuhaib Mohammed1 aTiejun Cheng1 aEvan Bolton1 aIrene Papatheodorou1 aLincoln Stein1 aDoreen Ware1 aPankaj Jaiswal00aPlant Reactome: a knowledgebase and resource for comparative pathway analysis. aD1093-D11030 v483 a
Plant Reactome (https://plantreactome.gramene.org) is an open-source, comparative plant pathway knowledgebase of the Gramene project. It uses Oryza sativa (rice) as a reference species for manual curation of pathways and extends pathway knowledge to another 82 plant species via gene-orthology projection using the Reactome data model and framework. It currently hosts 298 reference pathways, including metabolic and transport pathways, transcriptional networks, hormone signaling pathways, and plant developmental processes. In addition to browsing plant pathways, users can upload and analyze their omics data, such as the gene-expression data, and overlay curated or experimental gene-gene interaction data to extend pathway knowledge. The curation team actively engages researchers and students on gene and pathway curation by offering workshops and online tutorials. The Plant Reactome supports, implements and collaborates with the wider community to make data and tools related to genes, genomes, and pathways Findable, Accessible, Interoperable and Re-usable (FAIR).
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