TY - JOUR
AU - Irene Papatheodorou
AU - Nuno Fonseca
AU - Maria Keays
AU - Amy Tang
AU - Elisabet Barrera
AU - Wojciech Bazant
AU - Melissa Burke
AU - Anja Füllgrabe
AU - Alfonso Fuentes
AU - Nancy George
AU - Laura Huerta
AU - Satu Koskinen
AU - Suhaib Mohammed
AU - Matthew Geniza
AU - Justin Preece
AU - Pankaj Jaiswal
AU - Andrew Jarnuczak
AU - Wolfgang Huber
AU - Oliver Stegle
AU - Juan Vizcaino
AU - Alvis Brazma
AU - Robert Petryszak
AB - Expression Atlas (http://www.ebi.ac.uk/gxa) is an added value database that provides information about gene and protein expression in different species and contexts, such as tissue, developmental stage, disease or cell type. The available public and controlled access data sets from different sources are curated and re-analysed using standardized, open source pipelines and made available for queries, download and visualization. As of August 2017, Expression Atlas holds data from 3,126 studies across 33 different species, including 731 from plants. Data from large-scale RNA sequencing studies including Blueprint, PCAWG, ENCODE, GTEx and HipSci can be visualized next to each other. In Expression Atlas, users can query genes or gene-sets of interest and explore their expression across or within species, tissues, developmental stages in a constitutive or differential context, representing the effects of diseases, conditions or experimental interventions. All processed data matrices are available for direct download in tab-delimited format or as R-data. In addition to the web interface, data sets can now be searched and downloaded through the Expression Atlas R package. Novel features and visualizations include the on-the-fly analysis of gene set overlaps and the option to view gene co-expression in experiments investigating constitutive gene expression across tissues or other conditions.
BT - Nucleic acids research
C1 - http://www.ncbi.nlm.nih.gov/pubmed/29165655?dopt=Abstract
DA - 2018 Jan 04
DO - 10.1093/nar/gkx1158
IS - D1
J2 - Nucleic Acids Res.
LA - eng
N2 - Expression Atlas (http://www.ebi.ac.uk/gxa) is an added value database that provides information about gene and protein expression in different species and contexts, such as tissue, developmental stage, disease or cell type. The available public and controlled access data sets from different sources are curated and re-analysed using standardized, open source pipelines and made available for queries, download and visualization. As of August 2017, Expression Atlas holds data from 3,126 studies across 33 different species, including 731 from plants. Data from large-scale RNA sequencing studies including Blueprint, PCAWG, ENCODE, GTEx and HipSci can be visualized next to each other. In Expression Atlas, users can query genes or gene-sets of interest and explore their expression across or within species, tissues, developmental stages in a constitutive or differential context, representing the effects of diseases, conditions or experimental interventions. All processed data matrices are available for direct download in tab-delimited format or as R-data. In addition to the web interface, data sets can now be searched and downloaded through the Expression Atlas R package. Novel features and visualizations include the on-the-fly analysis of gene set overlaps and the option to view gene co-expression in experiments investigating constitutive gene expression across tissues or other conditions.
PY - 2018
SP - D246
EP - D251
T2 - Nucleic acids research
TI - Expression Atlas: gene and protein expression across multiple studies and organisms.
VL - 46
SN - 1362-4962
ER -